Huge and recurrent undifferentiated carcinoma with osteoclastlike giant cells of the pancreas

Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of the pancreas (UCOGCP) is a rare pancreatic tumor originated from pancreatic ductal epithelium. It is considered as a variant subtype of pancreatic ductal adenocarcinoma (PDAC), accounting for less than 1% of pancreatic malignant neoplasms (1,2). Most UCOGCPs are found to have a large tumor upon detection, which are frequently unresectable. Even treated with surgical removal, UCOGCP has a tendency of early recurrence. Hereby we report a case of a large UCOGCP with recurrence shortly after surgical excision.