@article{QIMS672,
author = {Pu-Xuan Lu and Ying-Ying Deng and Shui-Teng Liu and Yan Liu and Ying-Xia Liu and Yi-Xiang J Wang and Wen-Ke Zhu and Xiao-Hua Le and Wei-Ye Yu and Bo-Ping Zhou},
title = {Correlation between imaging features of Pneumocystis Jiroveci Pneumonitis (PCP), CD4+ T lymphocyte count, and plasma HIV viral load: A study in 50 consecutive AIDS patients},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {2},
number = {2},
year = {2012},
keywords = {},
abstract = {Purpose: To investigate the imaging manifestations of Pneumocystis Jiroveci Pneumonitis (PCP) in AIDS patients, and the correlation between imaging features, CD4+ lymphocyte count, and plasma HIV viral load.
Material and methods: A total of consecutive 50 AIDS patients with PCP were review retrospectively. Chest CT manifestations, CD4+ lymphocyte count, and plasma HIV viral load were analyzed to investigate their correlation.
Results: PCP chest CT manifestations included ground-glass opacities dominated in 28 cases (28/50, 56%), lung cysts dominated in 10 cases (10/50, 20%), consolidation dominated in 6 cases (6/50, 12%), interstitial lesion dominated in 3 cases (3/50, 6%), and mixed lesions in 3 cases (3/50, 6%). In these 50 patients, CD4+ lymphocyte count ranged from 2~373 cells/μL. Plasma HIV viral load ranged from 500~5.28×107 copies/mL. CD4+ lymphocyte count in ground-glass opacities dominated patients was higher than that of lung cyst dominated patients (P<0.05). Plasma virus load of lung cysts dominated PCP patients was higher than that of consolidation dominated patients (P<0.05).
Conclusions: The typical chest imaging features of PCP in AIDS patients included lung ground-glass opacities and lung cysts. The chest imaging features were correlated with CD4+ T lymphocyte count and plasma HIV viral load.},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/672}
}