@article{QIMS6092,
author = {Sarah L. Pownder and Parina H. Shah and Hollis G. Potter and Matthew F. Koff},
title = {The effect of freeze-thawing on magnetic resonance imaging T2* of freshly harvested bovine patellar tendon},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {5},
number = {3},
year = {2015},
keywords = {},
abstract = {Background: Analysis of fresh specimens in research studies is ideal; however, it is often necessary to freeze samples for evaluation at a later time. Limited evaluation of the effect of freeze-thawing of tendon tissue samples on inherent magnetic resonance imaging (MRI) parameters, such as ultrashort echo time (UTE) T2* values, have been performed to date.
Methods: This study performed UTE MRI on 14 bovine patellar tendons at harvest and after four consecutive freeze-thaw cycles.
Results: Results demonstrated a small but significant reduction (12%) in tendon T2* values after the first freeze thaw cycle, but not after successive cycles. Tendons from juvenile animals with open physes had a significant reduction of T2* following a single freeze thaw cycle, P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/6092}
}