@article{QIMS3771,
author = {Filippo Del Grande and Ney Tatizawa-Shiga and Sahar Jalali Farahani and Majid Chalian and Laura Marie Fayad},
title = {Chemical shift imaging: preliminary experience as an alternative sequence for defining the extent of a bone tumor},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {4},
number = {3},
year = {2014},
keywords = {},
abstract = {Objective: To investigate chemical shift imaging (CSI) with in-phase and opposed-phase (OP) gradientecho sequences as an alternative sequence to spin-echo T1 imaging for defining intra-medullary skeletal tumor extent.
Methods and materials: This retrospective HIPAA-compliant study was approved by our institutional institutional review board (IRB). Twenty-three subjects with histologically-proven tumors (17 appendicular, 6 axial) underwent magnetic resonance imaging (MRI) with T1-weighted spin echo (T1SE), fluid-sensitive, CSI, and contrast-enhanced T1 sequences. One observer recorded intra-medullary tumor extent (millimeters), with 153 total measurements on each sequence. Red marrow grade [0 (none), 1 (75%)] in each bone was recorded. Tumor extent on different sequences was compared (Student’s t-test); the impact of red marrow grade on measurements was assessed (Spearman’s correlation coefficient).
Results: There was good agreement between measurements of tumor extent on T1SE and CSI sequences in all cases (T1SE-CSI measurement difference range 0-13.2 mm, P>0.05). Measurements from other sequences were significantly different from those of T1SE (P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/3771}
}