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Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry

  
@article{QIMS2909,
	author = {Roberto Reif and Zhongwei Zhi and Suzan Dziennis and Alfred L. Nuttall and Ruikang K. Wang},
	title = {Changes in cochlear blood flow in mice due to loud sound exposure measured with Doppler optical microangiography and laser Doppler flowmetry},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {3},
	number = {5},
	year = {2013},
	keywords = {},
	abstract = {In this work we determined the contributions of loud sound exposure (LSE) on cochlear blood flow (CoBF) in an in vivo anesthetized mouse model. A broadband noise system (20 kHz bandwidth) with an intensity of 119 dB SPL, was used for a period of one hour to produce a loud sound stimulus. Two techniques were used to study the changes in blood flow, a Doppler optical microangiography (DOMAG) system; which can measure the blood flow within individual cochlear vessels, and a laser Doppler flowmetry (LDF) system; which averages the blood flow within a volume (a hemisphere of ~1.5 mm radius) of tissue. Both systems determined that the blood flow within the cochlea is reduced due to the LSE stimulation.},
	issn = {2223-4306},	url = {https://qims.amegroups.org/article/view/2909}
}