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Semi-quantitative analysis of 99mTc-sestamibi retention level for preoperative differential diagnosis of parathyroid carcinoma

  
@article{QIMS27253,
	author = {Min Zhang and Lihao Sun and Weiwei Rui and Rui Guo and Huihui He and Ying Miao and Hongping Meng and Jianmin Liu and Biao Li},
	title = {Semi-quantitative analysis of 99mTc-sestamibi retention level for preoperative differential diagnosis of parathyroid carcinoma},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {9},
	number = {8},
	year = {2019},
	keywords = {},
	abstract = {Background: To investigate the role of 99mTc-labeled sestamibi (99mTc-MIBI) retention level in the assessment of malignant potential of parathyroid lesions.
Methods: Twenty patients with parathyroid carcinomas and forty controls with benign parathyroid lesions who underwent preoperatively 99mTc-MIBI dual-phase planar and SPECT/CT imaging were retrospectively enrolled in this study. The mean and peak of retention index (RImean and RIpeak) were measured for evaluating the retention level of 99mTc-MIBI in the parathyroid lesions. Diagnostic accuracies of RI for differentiating malignant parathyroid lesions from benign ones were assessed by receiver operating characteristic analyses (area under the curve; AUC).
Results: RIpeak (AUC =0.87, P},
	issn = {2223-4306},	url = {https://qims.amegroups.org/article/view/27253}
}