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Designing visible-light optical coherence tomography towards clinics

	author = {Xiao Shu and Lisa Beckmann and Yuanbo Wang and Ian Rubinoff and Katie Lucy and Hiroshi Ishikawa and Gadi Wollstein and Amani A. Fawzi and Joel S. Schuman and Roman V. Kuranov and Hao F. Zhang},
	title = {Designing visible-light optical coherence tomography towards clinics},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {9},
	number = {5},
	year = {2019},
	keywords = {},
	abstract = {Background: The capabilities of visible-light optical coherence tomography (vis-OCT) in noninvasive anatomical and functional retinal imaging have been demonstrated by multiple groups in both rodents and healthy human subjects. Translating laboratory prototypes to an integrated clinical-environment-friendly system is required to explore the full potential of vis-OCT in disease management.
Methods: We developed and optimized a portable vis-OCT system for human retinal imaging in clinical settings. We acquired raster- and circular-scan images from both healthy and diseased human eyes. 
Results: The new vis-OCT provided high-quality retinal images of both subjects without any known eye diseases and patients with various retinal diseases, including retinal occlusive disease and diabetic retinopathy (DR) over a broad range of ages.
Conclusions: A newly designed vis-OCT system is sufficiently optimized to be suited for routine patients’ examinations in clinics. Vis-OCT has the potential to add new anatomical and functional imaging capabilities to ophthalmic clinical care.},
	issn = {2223-4306},	url = {}