@article{QIMS25201,
author = {Sock Keow Tan and Kwan Hoong Ng and Chai Hong Yeong and Raja Rizal Azman Raja Aman and Fadhli Mohamed Sani and Yang Faridah Abdul Aziz and Zhonghua Sun},
title = {Personalized administration of contrast medium with high delivery rate in low tube voltage coronary computed tomography angiography},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {9},
number = {4},
year = {2019},
keywords = {},
abstract = {Background: High delivery rate is an important factor in optimizing contrast medium administration in coronary computed tomography angiography (CCTA). A personalized contrast volume calculation algorithm incorporating high iodine delivery rate (IDR) can reduce total iodine dose (TID) and produce optimal vessel contrast enhancement (VCE) in low tube voltage CCTA. In this study, we developed and validated an algorithm for calculating the volume of contrast medium delivered at a high rate for patients undergoing retrospectively ECG-gated CCTA with low tube voltage protocol.
Methods: The algorithm for an IDR of 2.22 gIs−1 was developed based on the relationship between VCE and contrast volume in 141 patients; test bolus parameters and characteristics in 75 patients; and, tube voltage in a phantom study. The algorithm was retrospectively tested in 45 patients who underwent retrospectively ECG-gated CCTA with a 100 kVp protocol. Image quality, TID and radiation dose exposure were compared with those produced using the 120 kVp and routine contrast protocols.
Results: Age, sex, body surface area (BSA) and peak contrast enhancement (PCE) were significant predictors for VCE (P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/25201}
}