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Predicting peritumoral Glisson’s sheath invasion of intrahepatic cholangiocarcinoma with preoperative CT imaging

   
@article{QIMS23285,
	author = {Yingfan Mao and Yong Zhu and Yudong Qiu and Weiwei Kong and Liang Mao and Qun Zhou and Jun Chen and Jian He},
	title = {Predicting peritumoral Glisson’s sheath invasion of intrahepatic cholangiocarcinoma with preoperative CT imaging},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {9},
	number = {2},
	year = {2019},
	keywords = {},
	abstract = {Background: To investigate the differences of clinicopathological characteristics and computed tomography (CT) features between intrahepatic cholangiocarcinomas (ICC) with and without peritumoral Glisson’s sheath invasion (PGSI), and to construct a nomogram to predict PGSI of ICCs preoperatively. 
Methods: The clinicopathological characteristics and CT features of 84 ICCs were retrospectively analyzed and compared between ICCs with (30/84, 35.7%) and without PGSI (54/84, 64.3%). Multivariate logistic regression analysis was used to identify preoperative independent predictors of PGSI in ICCs. A nomogram was constructed to predict PGSI preoperatively.
Results: ICCs with and without PGSI differed significantly in the presence of abdominal pain, serum carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) levels, TNM and T stages, tumor location, intratumoral calcifications, intrahepatic bile duct dilatation, intrahepatic bile duct calculus, morphologic type and dynamic enhancement pattern on CT images (all P},
	issn = {2223-4306},	url = {https://qims.amegroups.org/article/view/23285}
}