@article{QIMS19564,
author = {Zheng Chen and Gang Zhang and Alexander Lerner and An-Hui Wang and Bo Gao and Jie Liu},
title = {Risk factors for poor outcome in posterior reversible encephalopathy syndrome: systematic review and meta-analysis},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {8},
number = {4},
year = {2018},
keywords = {},
abstract = {Background: The roles of clinical etiology and symptoms, imaging findings and biochemical parameters in predicting the prognosis of posterior reversible encephalopathy syndrome (PRES) have not been well-characterized. We perform a meta-analysis of all published studies to assess the value of various risk factors in predicting the prognosis of PRES.
Methods: Searches of the PubMed, EMBASE, Cochrane Library, and Web of Science databases were performed to identify the eligible studies. The odds ratios (ORs) with their corresponding 95% confidence interval (CI) for related risk factors were used to calculate the pooled estimates of the outcomes.
Results: Six studies with 448 cases were included in the meta-analysis. Hemorrhage was associated with high risk for poor outcome in patients with PRES. Toxemia of pregnancy (pre-eclampsia/eclampsia) was associated with improved outcome in PRES patients. Cytotoxic edema was noted to be related to poor outcome, but did not show statistical significance. The pooled OR for hemorrhage, pre-eclampsia/eclampsia, cytotoxic edema was 4.93 (95% CI: 3.94–6.17; P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/19564}
}