@article{QIMS155643,
author = {Meng Zhu and Huan Xu and Yidong Huang and Hualin Yan and Xiangfeng Zeng and Buyun Ma and Juxian Liu},
title = {Ultrasound features for pediatric testicular lesions: 20 years of ultrasound practice interpreted through the 2022 WHO Classification},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {16},
number = {7},
year = {2026},
keywords = {},
abstract = {Background: Testicular lesions are rare in pediatric populations. The World Health Organization standardized the classification of testicular tumors for urological and male genital tumors in 2022. Ultrasound is highly sensitive in detecting testicular lesions in children; however, the ultrasound features that distinguish malignant from benign lesions remain unclear. We aimed to identify ultrasound features that differentiate benign and malignant testicular lesions in pediatric patients. In addition, we evaluated the role of ultrasound in pediatric testicular tumors based on the new guidelines.Methods: We retrospectively reviewed the clinical data and ultrasound images of 84 testicular lesions in 79 pediatric patients aged 0–18 years (≤216 months), who underwent testicular sonography between April 2004 and October 2023 at West China Hospital. Prepuberty was defined as 0–12 years of age. Univariate and multivariate logistic regression analyses were conducted to compare ultrasound features between benign and malignant tumors across all 84 lesions, 66 primary tumors, and 65 prepubertal lesions. Continuous variables were compared between groups using the Mann-Whitney U test, and Fisher’s exact test was used for categorical variables.Results: Univariate analysis showed that among the 84 total lesions, the malignant group exhibited a more diffuse lesion range compared with the benign group (P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/155643}
}