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Comparison of dosimetric parameters and delivery accuracy between conformal radiotherapy-intensity modulated radiotherapy-combined and intensity-modulated radiotherapy planning for central lung cancer patients receiving stereotactic body radiotherapy

   
@article{QIMS155062,
	author = {Yan Shao and Jindong Guo and Yanhua Duan and Ying Huang and Aihui Feng and Hua Chen and Hao Wang and Hengle Gu and Zhenjiong Shen and Zhiyong Xu},
	title = {Comparison of dosimetric parameters and delivery accuracy between conformal radiotherapy-intensity modulated radiotherapy-combined and intensity-modulated radiotherapy planning for central lung cancer patients receiving stereotactic body radiotherapy},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {16},
	number = {7},
	year = {2026},
	keywords = {},
	abstract = {Background: With the development of technology, stereotactic body radiotherapy (SBRT) has been increasingly applied in the treatment of patients with central lung cancer. Three-dimensional conformal radiotherapy (3DCRT) and intensity-modulated radiotherapy (IMRT) are common SBRT techniques for lung cancer. Although 3DCRT plans have low complexity, the quality of such plans is highly dependent on the experience of the planner. IMRT plans can provide better organ-at-risk (OAR) sparing, but they are associated with a high degree of modulation. Therefore, an SBRT planning strategy that combines the advantages of 3DCRT and IMRT has been developed. The purpose of this study was to investigate the differences in dosimetric parameters and delivery accuracy between CRT-IMRT-combined (Co-CRIM) and IMRT plans for central lung cancer patients treated with SBRT.Methods: Twenty patients were retrospectively included in this study. Four plans were designed for each patient. Co-CRIM-E and IMRT-E plans were designed based on Co-CRIM and IMRT, and delivered with Varian Edge. Co-CRIM-T and IMRT-T plans were designed based on Co-CRIM and IMRT, and delivered with Varian TrueBeam. Dosimetric parameters were compared between Co-CRIM-E and IMRT-E plans, as well as between Co-CRIM-T and IMRT-T plans. Monitor unit (MU), modulation factor (MF) and gamma (γ) passing rate were calculated for each plan. Paired-samples t-test was used to check the differences between datasets and P},
	issn = {2223-4306},	url = {https://qims.amegroups.org/article/view/155062}
}