@article{QIMS155012,
author = {Yanrong Yang and Anjie Chen and Yuting Wang and Shuhua Shi and Hongyan Chen and Yongzhong Li and Jiaojiao Zhou},
title = {The application of shear wave elastography in monitoring renal allografts},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {16},
number = {7},
year = {2026},
keywords = {},
abstract = {Background: Follow-up for renal transplant recipients depends on laboratory tests for the monitoring of renal function. Ultrasound shear wave elastography (SWE), as a noninvasive technique, can measure renal allograft stiffness, offering a potential direct indicator of the allograft’s functional status. This study aimed to establish a model for monitoring and assessing renal allograft function by combining SWE imaging of renal allografts with laboratory indicators to assist in monitoring renal function.Methods: Ultrasound SWE was performed in renal transplant recipients who met the inclusion and exclusion criteria during routine follow-up ultrasound examinations at West China Hospital of Sichuan University between December 2021 and August 2022. The stiffness values were recorded as shear wave velocity (SWV). Stiffness was measured three times in each patient, and the median of the three measurements was used for subsequent analysis. The data collected comprised relevant laboratory test indicators—including serum creatinine (Scr), estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN), serum uric acid (UA), serum cystatin C (Cys C), cholesterol, and albumin—and Doppler parameters—including the systolic peak velocity, end-diastolic flow velocity, and resistance index from the main, segmental, interlobar, and arcuate arteries of the renal allograft. Correlation analysis was conducted between SWV values and the collected parameters. Univariate and multivariate analyses were performed to identify factors associated with impaired allograft function, defined as an eGFR },
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/155012}
}