@article{QIMS154981,
author = {Yun-Nan Li and Shi-Liang Li and Qiao-Yin Zhou},
title = {Comparison of ultrasound-guided needle-knife release of the transverse carpal ligament with glucocorticoid injection in the treatment of carpal tunnel syndrome: a randomized trial},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {16},
number = {7},
year = {2026},
keywords = {},
abstract = {Background: Ultrasound-guided needle-knife release of the transverse carpal ligament (TCL) has the potential to treat mild-to-moderate carpal tunnel syndrome (CTS). This study aimed to compare the clinical efficacy and safety of ultrasound-guided needle-knife release of the TCL with those of glucocorticoid injection therapy.Methods: A total of 27 patients with mild or moderate CTS, involving 32 carpal tunnels, were enrolled between September 2025 and January 2026. They were randomly assigned to either the ultrasound-guided needle-knife therapy group (Group T, 17 carpal tunnels) or the ultrasound-guided glucocorticoid injection group (Group C, 15 carpal tunnels). Functional scores, Numerical Rating Scale (NRS) numbness and pain scores, Boston carpal tunnel questionnaire (BCTQ) scale scores, and 36-Item Short Form Health Survey (SF-36) scale scores were recorded and compared between groups at baseline, 1 month, and 3 months post-treatment. Clinical efficacy rates were assessed using the Kelly criteria.Results: Compared with baseline, at 1 and 3 months post-treatment, Group T showed a significant improvement in carpal tunnel function scores (P=0.011, P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/154981}
}