@article{QIMS154728,
author = {Yuchen Shen and Jie Liu and Yaqing He and Rongchen Wei and Rui Wang and Yichao Yan and Mingxin Liu and Bo Song and Bailin Wu},
title = {Reversible left ventricular trabecular remodeling after bariatric surgery in obesity: a prospective cohort study using quantitative cardiac MRI},
journal = {Quantitative Imaging in Medicine and Surgery},
volume = {16},
number = {7},
year = {2026},
keywords = {},
abstract = {Background: Obesity is associated with structural and functional cardiac remodeling; however, its quantitative imaging characteristics and the role of left ventricular trabeculation remain incompletely understood. This study aimed to characterize left ventricular trabeculation using multi-parametric cardiac magnetic resonance in patients with obesity, explore its association with subclinical cardiac dysfunction, and evaluate longitudinal changes following bariatric surgery.Methods: In this prospective single-center study, 30 patients with severe obesity underwent cardiac magnetic resonance imaging before and approximately 12 months after bariatric surgery, along with 30 age- and sex-matched healthy controls. Quantitative parameters included the non-compacted to compacted layer ratio (NC/C), trabecular mass fraction, left ventricular mass, left ventricular ejection fraction, global longitudinal strain, and diastolic filling indices. Left ventricular ejection fraction indexed to body surface area was analyzed as an exploratory parameter. Mediation analysis was performed to assess whether trabeculation statistically explained part of the association between body mass index and cardiac function, adjusting for age, sex, and blood pressure.Results: Compared with controls, patients with obesity showed significantly higher NC/C (1.68±0.24 vs. 1.11±0.19, P},
issn = {2223-4306}, url = {https://qims.amegroups.org/article/view/154728}
}