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Lumbar intervertebral discs T2 relaxometry and T1ρ relaxometry correlation with age in asymptomatic young adults

   
@article{QIMS11253,
	author = {Rafael Menezes-Reis and Carlos E. Garrido Salmon and Gustavo P. Bonugli and Debora Mazoroski and Mauricio H. Tamashiro and Leonor G. Savarese and Marcello Henrique Nogueira-Barbosa},
	title = {Lumbar intervertebral discs T2 relaxometry and T1ρ relaxometry correlation with age in asymptomatic young adults},
	journal = {Quantitative Imaging in Medicine and Surgery},
	volume = {6},
	number = {4},
	year = {2016},
	keywords = {},
	abstract = {Background: To investigate the detection of intervertebral disc (IVD) composition aging-related changes using T2 and T1ρ relaxometry in vivo in asymptomatic young adults. 
Methods: We recruited ninety asymptomatic and young adults (42 men and 48 women) between 20 and 
40 years old. T2 and T1ρ lumbar spine mappings were acquired using 1.5 T magnetic resonance imaging (MRI) scanner. Two independent observers manually segmented 450 lumbar discs in all slices. They also performed sub region segmentation of annulus fibrosus (AF) and nucleus pulposus (NP) at the central MRI sagittal slices. 
Results: There was no difference between men and women for T2 (P=0.37) or T1ρ relaxometry (P=0.97). There was a negative correlation between age (20–40 years) and IVD T2 relaxation time of the whole disc (r=−0.30, P},
	issn = {2223-4306},	url = {https://qims.amegroups.org/article/view/11253}
}